Micro and Nano-printing of 3D Designer Scaffolds for Tissue Engineering
Shaochen Chen, Ph.D.
Professor, NanoEngineering Department and Institute of Engineering in Medicine University of California, San Diego, USA
The goal of our laboratory is to develop micro- and nano-scale printing techniques for the direct-write of 3D designer scaffolds used for tissue engineering and regenerative medicine. The breadth of our focus spans the full range of physical dimensions (from nano- to micro- to meso-scale), time span (from femtoseconds to days), and biological dimensions (from molecular to cellular to tissue). In this talk, I will discuss my laboratory’s recent research efforts in femtosecond laser stereolithography, DMD projection printing, and nanoimprinting to create 3D scaffolds using a variety of biomaterials. These 3D biomaterials are functionalized with precise control of micro-architecture, mechanical properties (e.g. stiffness and Poisson’s ratio), and growth factor. Such biomaterials provide enhanced knowledge of cell-material interactions at nano and microscales in response to integrated physical and chemical stimuli. These fundamental studies allow us to create advanced therapeutic systems for tissue engineering and regenerative medicine.
Dr. Shaochen Chen is a Professor in the Nanoengineering Department at the University of California, San Diego (UCSD). He is also a faculty member of the Institute of Engineering in Medicine at UCSD. Before joining UCSD, Dr. Chen had been a Professor and a Pearlie D. Henderson Centennial Endowed Faculty Fellow in Engineering in the Mechanical Engineering Department at the University of Texas at Austin from 2001 to 2010. Between 2008 and 2010, he served as the Program Director for the Nanomanufacturing Program in the US National Science Foundation (NSF). Dr. Chen’s primary research interests include: biomaterials and biofabrication, nanomanufacturing, regenerative medicine, tissue engineering, laser and nanophotonics. Dr. Chen has published 90 papers in top journals such as Nano Letters, Biomaterials and Advanced Materials, 12 book/book chapters, and 47 conference papers.
Among his numerous awards, Dr. Chen received the CAREER award from NSFand Young Investigator award from the Office of Naval Research (ONR), the most prestigious awards to young faculty in the US. As an active member in his professional community, Dr. Chen is a Fellow of the American Society of Mechanical Engineers (ASME), Fellow of the International Society for Optics and Photonics (SPIE), and Fellow of the American Association for the Advancement of Science (AAAS).