青年科学家学术论坛
第三讲
(2013年9月12日)
报告题目:基于微流控和纳米颗粒的生物检测
报 告 人:蒋兴宇(国家纳米科学中心)
报告地点:北京大学微纳电子大厦350会议室
报告时间:9月12日晚上7:30-9:30
简历:蒋兴宇博士是国家纳米科学中心研究员。蒋兴宇在美国芝加哥大学取得了化学学士学位(1999年),在哈佛大学取得了化学博士学位(2004年),并在哈佛大学进行了博士后研究(2004~2005年)。在哈佛期间师从美国科学院/工程院院士George Whitesides教授。2005年回国后获得 “中国化学会-威立出版社青年化学论文奖”、人类前沿科学项目“青年科学奖”。获得国家自然科学基金委员会“国家杰出青年基金”(2010)、2012年入选中组部首批“青年拔尖人才计划”、科技部 “973/863”、中科院“百人计划”等资助。主要研究方向是纳米生物医学。近期代表性论文:
1. Highly Robust, Recyclable Displacement Assay for Mercuric Ions in Aqueous Solutions and Living Cells, Liu D., Wang S., Swierczewska M., Huang X., Bhirde, A, Sun J., Wang Z., Yang M,, Jiang X.Y., and Chen X., ACS Nano, 6 (12) 10999-1008 (2012).
2. Resettable, multi-readout logic gates based on controllably reversible aggregation of gold nanoparticles, Liu, D., Chen, W., Sun, K., Deng, K., Zhang, W., Wang, Z., Jiang, X.Y. Angew. Chem. Int. Ed. 50, 4103-4107 (2011).
3. Copper-mediated amplification allows readout of immunoassays by the naked Eye, Qu,W., Liu, Y., Liu, D., Wang, Z, Jiang X.Y. Angew. Chem. Int. Ed. 50, 3442-3445 (2011).
4. Small-molecule capped gold nanoparticles as potent antibacterial agents that target Gram-negative bacteria. Zhao, Y.Y., Tian, Y., Cui, Y., Liu, W.W, Ma, W.shun and Jiang, X.Y., J. Am. Chem. Soc., 132, 12349-12356 (2010).
5. Loop-Mediated isothermal amplification integrated on microfluidic chips for Point-of-Care quantitative detection of pathogens. Fang, X.E., Liu, Y.Y., Kong, J.L., Jiang, X.Y., Anal. Chem., 82 (7), 3002?3006 (2010).
6. Patterning multiple types of mammalian cells for modeling three types of naturally occurring cell-cell interactions. Chen, Z.L., Li, Y., Liu, W.W., Zhang, D.Z., Zhao, Y.Y., Yuan, B., Jiang, X.Y., Angew. Chem. Int. Ed., 48(44), 8303-8305 (2009).
7. Using azobenezene-embedded self-assembled monolayers to reversibly control cell adhesion. Liu, D.B., Xie, Y.Y., Shao, H.W., Jiang, X.Y., Angew. Chem. Int. Ed., 48(24), 4406-4408 (2009).
8. Visual detection of copper(II) by azide- and alkyne-functionalized gold nanoparticles using click chemistry. Zhou, Y., Wang, S.X., Zhang, K., Jiang, X.Y., Angew. Chem. Int. Ed., 47 (39), 7454-7456 (2008).
9. Electrospun nanofibrous membranes: a novel solid substrate for microfluidic immunoassays for HIV. Yang, D.Y., Niu, X., Liu, Y.Y., Wang, Y., Gu, X., Song, L.S., Zhao, R., Ma, L.Y., Shao, Y.M., Jiang X.Y., Adv. Mater., 20 (24), 4770-4775 (2008).
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